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Article

Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn's Disease.

BioMed research international - 1 Jan 2015

Urabe Shigetoshi, Isomoto Hajime, Ishida Tetsuya, Maeda Kazumi, Inamine Tatsuo, Kondo Shinji, Higuchi Norihide, Sato Kayoko, Uehara Ryohei, Yajima Hiroyuki, Machida Haruhisa, Chen Chun Chuan, Fukuda Yasuhiro, Takeshima Fuminao, Nakao Kazuhiko, Tsukamoto Kazuhiro

Abstract excerpt

BACKGROUND: We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 signaling pathway with response to IFX after 1 year of treatment. METHODS: A total of 103 patients were divided into two...

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Identifiers

PMID: 26558270
DOI: 10.1155/2015/416838
PMCID: PMC4628975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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