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Article

Th17-related genes and celiac disease susceptibility.

PloS one - 1 Jan 2012

Medrano Luz María, García-Magariños Manuel, Dema Bárbara, Espino Laura, Maluenda Carlos, Polanco Isabel, Figueredo M Ángeles, Fernández-Arquero Miguel, Núñez Concepción

Abstract excerpt

Th17 cells are known to be involved in several autoimmune or inflammatory diseases. In celiac disease (CD), recent studies suggest an implication of those cells in disease pathogenesis. We aimed at studying the role of genes relevant for the Th17 immune response in CD susceptibility. A total of 101 single nucleotide polymorphisms (SNPs), mainly selected to cover most of the variability present in 16 Th17-related...

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Source

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Identifiers

PMID: 22359581
DOI: 10.1371/journal.pone.0031244
PMCID: PMC3281077

Genes

CCR6
JAK2
RORC
SOCS3
STAT3
TBX21
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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