Article
Identification of single nucleotide polymorphisms in the TNFRSF17 gene and their association with gastrointestinal disorders.
Molecules and cells - 1 Jan 2010
Chae Soo-Cheon, Yu Ji-In, Oh Gyung-Jae, Choi Chang-Soo, Choi Suck-Chei, Yang Yun-Sik, Yun Ki-Jung
Abstract excerpt
TNFRSF17 is preferentially expressed in mature B lymphocytes, and may be important for the development of B cells. TNFRSF17 is selected as a candidate susceptibility gene to IBD pathogenesis by our cDNA microarray analysis, and we showed the specific expression of TNFRSF17 in resting and activated CD19(+) cells obtained from human blood. We identified four SNPs (g-1729G>A, g.2295T>C, g.2445G>A and g.2493G>A) and...
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