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Article

Role of TNFRSF1B polymorphisms in the response of Crohn's disease patients to infliximab.

Human immunology - 1 Jan 2014

Medrano L M, Taxonera C, Márquez A, Barreiro-de Acosta M, Gómez-García M, González-Artacho C, Pérez-Calle J L, Bermejo F, Lopez-Sanromán A, Martín Arranz M D, Gisbert J P, Mendoza J L, Martín J, Urcelay E, Núñez C

Abstract excerpt

Infliximab (IFX) is a valid treatment for Crohn's disease (CD), but a relevant percentage of patients do not benefit from this therapy. In the Japanese population, the response to IFX was associated with markers in the TNF receptor superfamily 1A (TNFRSF1A) and 1B (TNFRSF1B) genes. We aimed to replicate the association previously described in the Japanese population and to ascertain the role of TNF receptors as...

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Source

Identifiers

PMID: 24121042
DOI: 10.1016/j.humimm.2013.09.017

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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