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Article

Response to Infliximab in Crohn's Disease: Genetic Analysis Supporting Expression Profile.

Mediators of inflammation - 1 Jan 2015

Medrano Luz María, Taxonera Carlos, González-Artacho Cristina, Pascual Virginia, Gómez-García María, Barreiro-de Acosta Manuel, Pérez-Calle José L, Bermejo Fernando, López-Sanromán Antonio, Martín Arranz Dolores, Gisbert Javier P, Mendoza Juan Luis, Martín Javier, Núñez Concepción, Urcelay Elena

Abstract excerpt

Substantial proportion of Crohn's disease (CD) patients shows no response or a limited response to treatment with infliximab (IFX) and to identify biomarkers of response would be of great clinical and economic benefit. The expression profile of five genes (S100A8-S100A9, G0S2, TNFAIP6, and IL11) reportedly predicted response to IFX and we aimed at investigating their etiologic role through genetic association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26339133
DOI: 10.1155/2015/318207
PMCID: PMC4539178

Genes

TNFAIP6
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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