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Article

Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis

3 Aug 2016

Abstract excerpt

In this study we tested expression of tight junction proteins in human, mouse and rat and analyzed the localization of claudin-11 in testis of patients with normal and impaired spermatogenesis. Recent concepts generated in mice suggest that the stage-specifically expressed claudin-3 acts as a basal barrier, sealing the seminiferous epithelium during migration of spermatocytes. Corresponding mechanisms have never...

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PMID: 27486954
DOI: 10.1371/journal.pone.0160349

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