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Establishment, maintenance and functional integrity of the blood–testis barrier in organotypic cultures of fresh and frozen/thawed prepubertal mouse testes

13 Mar 2017

Abstract excerpt

STUDY QUESTION: Can the spatio-temporal formation of an intact blood-testis barrier (BTB), which is essential for the progression of spermatogenesis, be reproduced in cultures of fresh or frozen/thawed prepubertal mouse testes? SUMMARY ANSWER: Organotypic cultures allow the establishment and maintenance of major BTB components and the formation of a functional BTB in mouse testicular tissues. WHAT IS KNOWN...

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PMID: 28333312
DOI: 10.1093/molehr/gax017

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