Article
A pharmacogenomic study revealed an association between SLC6A4 and risperidone-induced weight gain in Chinese Han population.
Pharmacogenomics - 1 Nov 2015
Wang Fang, Mi Weifeng, Ma Wenbin, Ma Cuicui, Yang Yongfeng, Zhang Hongxing, Du Bo, Li Keqing, Liu Chenxing, Wang Lifang, Lu Tianlan, Zhang Hongyan, Lv Luxian, Zhang Dai, Yue Weihua
Abstract excerpt
AIM: We carried out a pharmacogenomic study in order to identify susceptible genes for antipsychotics induced weight gain within the Chinese Han population. MATERIALS & METHODS: We enrolled 216 patients with schizophrenia in our study. All of them underwent risperidone monotherapy, and fulfilled 4-week follow-up. Weight gain was measured before treatment and 4 weeks later. Seven hundred and sixty-eight SNPs from...
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