Article
Association study of NRXN3 polymorphisms with schizophrenia and risperidone-induced bodyweight gain in Chinese Han population.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2013
Hu Xiaofeng, Zhang Jishui, Jin Chao, Mi Weifeng, Wang Fang, Ma Wenbin, Ma Cuicui, Yang Yongfeng, Li Wenqiang, Zhang Hongxing, Du Bo, Li Keqing, Liu Chenxing, Wang Lifang, Lu Tianlan, Zhang Hongyan, Lv Luxian, Zhang Dai, Yue Weihua
Abstract excerpt
Recent researches have implicated that mutations in the neurexin-3 (NRXN3) gene on chromosome 14q24.3-q31.1 might play a role in addiction, autism, and obesity. In order to explore the association of NRXN3 polymorphisms with schizophrenia, we examined seven single nucleotide polymorphisms (SNPs) in NRXN3 spanning 1.33 Mb of this gene, in a Chinese Han sample of 1214 schizophrenic patients and 1517 healthy control...
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