Article
Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Dec 2015
Maritschnegg Elisabeth, Wang Yuxuan, Pecha Nina, Horvat Reinhard, Van Nieuwenhuysen Els, Vergote Ignace, Heitz Florian, Sehouli Jalid, Kinde Isaac, Diaz Luis A, Papadopoulos Nickolas, Kinzler Kenneth W, Vogelstein Bert, Speiser Paul, Zeillinger Robert
Abstract excerpt
PURPOSE: Type II ovarian cancer (OC) and endometrial cancer (EC) are generally diagnosed at an advanced stage, translating into a poor survival rate. There is increasing evidence that Müllerian duct cancers may exfoliate cells. We have established an approach for lavage of the uterine cavity to detect shed cancer cells. PATIENTS AND METHODS: Lavage of the uterine cavity was used to obtain samples from 65...
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