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Article

Liquid biopsy for diagnosing epithelial ovarian cancer: quantification of cell-free DNA and p53 mutational analysis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2025

Rajaram Shalini, Varma Aanchal, Gupta Bindiya, Kar Rajarshi, Arora Vinod Kumar, Jain Sandhya, Singh Lakhwinder

Abstract excerpt

OBJECTIVE: To isolate and quantify cell-free DNA, analysis for p53 mutations, and correlation with tumor burden in women with epithelial ovarian cancer compared with benign and borderline epithelial ovarian tumors. METHODS: In this case-control study, plasma samples of eligible women collected 1 hour before surgery and based on final histopathology, women with epithelial ovarian cancer recruited as cases and...

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Identifiers

PMID: 39878261
DOI: 10.1016/j.ijgc.2024.100022

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