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Article

Evaluation of mutations detected in uterine exfoliated cells as a diagnostic tool for endometrial cancer.

Gynecologic oncology - 1 Jul 2025

Yang Wenqing, Shen Yufei, Tian Yan, Xiao Xiao, Shao Zhuo, Xia Xuefeng, Li Lucia, Yang Siyu, Wen Xinxin, Liu Yingzhen, Qiu Minghui, Li Yi, Yi Xin, Liu Qian, Bai Jing, Wu Lisha, Zhang Yu

Abstract excerpt

OBJECTIVE: Endometrial cancer (EC) is a prevalent gynecological malignancy, yet current diagnostic methods are often invasive and inconvenient for patients. This study aimed to evaluate the potential of detecting somatic mutations in uterine exfoliation cells as a less-invasive diagnostic approach for EC. METHODS AND ANALYSIS: A total of 67 patients, including 67 cases of EC or endometrial atypical hyperplasia...

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PMID: 40411967
DOI: 10.1016/j.ygyno.2025.05.009

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