Article
Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers.
Science translational medicine - 9 Jan 2013
Kinde Isaac, Bettegowda Chetan, Wang Yuxuan, Wu Jian, Agrawal Nishant, Shih Ie-Ming, Kurman Robert, Dao Fanny, Levine Douglas A, Giuntoli Robert, Roden Richard, Eshleman James R, Carvalho Jesus Paula, Marie Suely Kazue Nagahashi, Papadopoulos Nickolas, Kinzler Kenneth W, Vogelstein Bert, Diaz Luis A
Abstract excerpt
Papanicolaou (Pap) smears have revolutionized the management of patients with cervical cancers by permitting the detection of early, surgically curable tumors and their precursors. In recent years, the traditional Pap smear has been replaced by a liquid-based method, which allows not only cytologic evaluation but also collection of DNA for detection of human papillomavirus, the causative agent of cervical cancer....
Topics
- DNA, Neoplasm
- Endometrial Neoplasms
- Female
- Humans
- Mutation
- Ovarian Neoplasms
- Papanicolaou Test
- Vaginal Smears