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Effect of genetic and environmental factors on protein biomarkers for common non-communicable disease and use of personally normalized plasma protein profiles (PNPPP).

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2015

Enroth Stefan, Bosdotter Enroth Sofia, Johansson Åsa, Gyllensten Ulf

Abstract excerpt

OBJECTIVE: To study the impact of genetic and lifestyle factors on protein biomarkers and develop personally normalized plasma protein profiles (PNPPP) controlling for non-disease-related variance. MATERIALS AND METHODS: Proximity extension assays were used to measure 145 proteins in 632 controls and 344 cases with non-communicable diseases. RESULTS: Genetic and lifestyle factors explained 20-88% of the variation...

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Identifiers

PMID: 26551787
DOI: 10.3109/1354750X.2015.1093546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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