Article

Proteomic prediction of disease largely reflects environmental risk exposure

2025-08-29

Abstract excerpt

Plasma proteomic signatures accurately predict disease risk, but our understanding of the mechanisms contributing to the predictive value of the proteome remains limited. Here, we characterized proteomic biomarkers of 19 age-related diseases, based on observational associations between 2,923 protein levels and incidence of these outcomes in the UK Biobank (N = 45,438). To identify the subset of these biomarkers th...

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Literature Corpus work: d49f4ac1-e494-531f-8907-e3678d27fbbc
DOI: 10.1101/2025.08.27.25334571

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