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Article

Next generation plasma proteome profiling to monitor health and disease.

Nature communications - 3 May 2021

Zhong Wen, Edfors Fredrik, Gummesson Anders, Bergström Göran, Fagerberg Linn, Uhlén Mathias

Abstract excerpt

The need for precision medicine approaches to monitor health and disease makes it important to develop sensitive and accurate assays for proteome profiles in blood. Here, we describe an approach for plasma profiling based on proximity extension assay combined with next generation sequencing. First, we analyze the variability of plasma profiles between and within healthy individuals in a longitudinal wellness...

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Identifiers

PMID: 33941778
DOI: 10.1038/s41467-021-22767-z
PMCID: PMC8093230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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