Article
Association between TGFBR2 gene polymorphism (rs2228048, Asn389Asn) and intracerebral hemorrhage in Korean population.
Immunological investigations - 1 Jan 2011
Lim Yun Hee, Jeong Yong Seol, Kim Su Kang, Kim Dong Hwan, Yun Dong Hwan, Yoo Seung Don, Kim Hee-Sang, Baik Hyung Hwan
Abstract excerpt
Transforming growth factor, beta receptor II (TGFBR2) is mainly expressed by neurons in the central nervous system, and reduced neuronal TGFBR2 signaling results in accelerated age-dependent neurodegeneration. To investigate whether TGFBR2 polymorphisms are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH), two single nucleotide polymorphisms (SNPs) of TGFBR2 gene (rs764522, -1444C/G;...
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