Article
Body Composition QTLs Identified in Intercross Populations Are Reproducible in Consomic Mouse Strains.
PloS one - 1 Jan 2015
Lin Cailu, Fesi Brad D, Marquis Michael, Bosak Natalia P, Theodorides Maria L, Avigdor Mauricio, McDaniel Amanda H, Duke Fujiko F, Lysenko Anna, Khoshnevisan Amin, Gantick Brian R, Arayata Charles J, Nelson Theodore M, Bachmanov Alexander A, Reed Danielle R
Abstract excerpt
Genetic variation contributes to individual differences in obesity, but defining the exact relationships between naturally occurring genotypes and their effects on fatness remains elusive. As a step toward positional cloning of previously identified body composition quantitative trait loci (QTLs) from F2 crosses of mice from the C57BL/6ByJ and 129P3/J inbred strains, we sought to recapture them on a homogenous...
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