Article
Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2001
Cheverud J M, Vaughn T T, Pletscher L S, Peripato A C, Adams E S, Erikson C F, King-Ellison K J
Abstract excerpt
The genetic basis of variation in obesity in human populations is thought to be owing to many genes of relatively small effect and their interactions. The LG/J by SM/J intercross of mouse inbred strains provides an excellent model system in which to investigate multigenic obesity. We previously mapped a large number of quantitative trait loci (QTLs) affecting adult body weight in this cross. We map body...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.