Article
Architecture of energy balance traits in emerging lines of the Collaborative Cross.
American journal of physiology. Endocrinology and metabolism - 1 Jun 2011
Mathes Wendy Foulds, Aylor David L, Miller Darla R, Churchill Gary A, Chesler Elissa J, de Villena Fernando Pardo-Manuel, Threadgill David W, Pomp Daniel
Abstract excerpt
The potential utility of the Collaborative Cross (CC) mouse resource was evaluated to better understand complex traits related to energy balance. A primary focus was to examine if genetic diversity in emerging CC lines (pre-CC) would translate into equivalent phenotypic diversity. Second, we mapped quantitative trait loci (QTL) for 15 metabolism- and exercise-related phenotypes in this population. We evaluated...
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