Article
Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2014
Spiezio Sabrina H, Amon Lynn M, McMillen Timothy S, Vick Cynthia M, Houston Barbara A, Caldwell Mark, Ogimoto Kayoko, Morton Gregory J, Kirk Elizabeth A, Schwartz Michael W, Nadeau Joseph H, LeBoeuf Renée C
Abstract excerpt
Metabolic diseases such as obesity and atherosclerosis result from complex interactions between environmental factors and genetic variants. A panel of chromosome substitution strains (CSSs) was developed to characterize genetic and dietary factors contributing to metabolic diseases and other biological traits and biomedical conditions. Our goal here was to identify quantitative trait loci (QTLs) contributing to...
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