An evolutionary stability perspective on oncogenesis control in mature T-cell populations.

Abstract excerpt

Here we present a mathematical model for the dynamics of oncogenesis control in mature T-cell populations within the blood and lymphatic system. T-cell homeostasis is maintained by clonal competition for trophic niches (survival signals stimulated through interactions with self-antigens bound to major histocompatibility molecules), where a clone is defined as the set of T cells carrying the same antigen specific...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinogenesis
• Share to Cell Cycle
• Share to Homeostasis