Article
Nuclear and mitochondrial DNAs microsatellite instability and mitochondrial DNA copy number in adenocarcinoma and squamous cell carcinoma of lung: a pilot study.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 2015
Lee Deok Heon, Lee Jae-Ho, Kim Dae-Kwang, Keum Dong Yoon
Abstract excerpt
Mitochondrial genetic changes are considered as a key molecular step of mutations in various cancers. To clarify the role of genetic instability in lung cancer, we analyzed clinicopathological characteristics and frequencies of nuclear and mitochondrial microsatellite instability (nMSI and mtMSI), and alteration of mitochondrial DNA copy number (mtCN) in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
