CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder.

doi:10.1192/bjp.bp.114.159806

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Article

CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder.

The British journal of psychiatry : the journal of mental science - 1 Feb 2016

Jakobsson Joel, Pålsson Erik, Sellgren Carl, Rydberg Frida, Ekman Agneta, Zetterberg Henrik, Blennow Kaj, Landén Mikael

Abstract excerpt

Several genome-wide association studies and case-control studies have associated the single nucleotide polymorphism (SNP) rs1006737, situated in CACNA1C encoding the alpha 1C subunit of the L-type voltage-gated calcium channel, with bipolar disorder and other psychiatric disorders. However, the causal pathway linking genetic variants in CACNA1C with increased risk for developing brain disorders remains unclear....

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PMID: 26541689
DOI: 10.1192/bjp.bp.114.159806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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