The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder.

doi:10.1111/acps.12073

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder.

Acta psychiatrica Scandinavica - 1 Nov 2013

Soeiro-de-Souza M G, Bio D S, Dias V V, Vieta E, Machado-Vieira R, Moreno R A

Abstract excerpt

OBJECTIVE: Calcium channels are important for converting electrical activity into biochemical events. A single nucleotide polymorphism (SNP) (rs1006737) in the CACNA1C gene has been strongly associated with increased risk for Bipolar disorder (BD) in genome-wide association studies. Recently, this same SNP has been reported to influence executive function in schizophrenia and controls, but it remains unclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alleles

Share to Bipolar Disorder

Share to Calcium Channels, L-Type

Share to Executive Function

Share to Neuropsychological Tests

Share to Risk

Share to Young Adult

Source

Open in PubMed

Identifiers

PMID: 23406546
DOI: 10.1111/acps.12073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder.PMID 23406546Read ↗

CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity.Semantic proximity Read ↗

Evidence for the impact of the CACNA1C risk allele rs1006737 on 2-year cognitive functioning in bipolar disorder.Semantic proximity Read ↗

CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls.Semantic proximity Read ↗

Genetic variation in CACNA1C affects brain circuitries related to mental illness.Semantic proximity Read ↗

Brain function in carriers of a genome-wide supported bipolar disorder variant.Semantic proximity Read ↗

Effects of the CACNA1C Risk Allele for Bipolar Disorder on Cerebral Gray Matter Volume in Healthy IndividualsSemantic proximity Read ↗

CACNA1C polymorphisms Impact Cognitive Recovery in Patients with Bipolar Disorder in a Six-week Open-label Trial.Semantic proximity Read ↗

Initial evidence for the role of CACNA1C on subcortical brain morphology in patients with bipolar disorder.Semantic proximity Read ↗

Genetic variation in CACNA1C, a gene associated with bipolar disorder, influences brainstem rather than gray matter volume in healthy individuals.Semantic proximity Read ↗

CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder.Semantic proximity Read ↗

Effects of the CACNA1C risk allele on neurocognition in patients with schizophrenia and healthy individuals.Semantic proximity Read ↗

Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.