Article
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study.
Bipolar disorders - 1 Mar 2013
Gonzalez Suzanne, Xu Chun, Ramirez Mercedes, Zavala Juan, Armas Regina, Contreras Salvador A, Contreras Javier, Dassori Albana, Leach Robin J, Flores Deborah, Jerez Alvaro, Raventós Henriette, Ontiveros Alfonso, Nicolini Humberto, Escamilla Michael
Abstract excerpt
OBJECTIVES: Through recent genome-wide association studies (GWASs), several groups have reported significant association between variants in the calcium channel, voltage-dependent, L-type, alpha 1C subunit (CACNA1C) and bipolar disorder (BP) in European and European-American cohorts. We performed a family-based association study to determine whether CACNA1C is associated with BP in the Latino population. METHODS:...
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