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Article

Association of CACNA1C polymorphisms with serum BDNF levels in bipolar disorder

18 Jul 2019

Abstract excerpt

Variation in the CACNA1C gene has been associated with bipolar disorder in several genome-wide association studies. This gene encodes the alpha 1C subunit of L-type voltage-gated calcium channels, which play an essential role in neurons. We analysed 39 biomarkers in either cerebrospinal fluid or serum in relation to six different CACNA1C variants in 282 patients with bipolar disorder and 90 controls. We report...

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PMID: 31317860
DOI: 10.1192/bjp.2019.173

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