Article
The Evolution and Structure of Atypical T Cell Receptors.
Results and problems in cell differentiation - 1 Jan 2015
Hansen Victoria L, Miller Robert D
Abstract excerpt
The T cell receptor structure and genetic organization have been thought to have been stable in vertebrate evolution relative to the immunoglobulins. For the most part, this has been true and the content and organization of T cell receptor genes has been fairly conserved over the past 400 million years of gnathostome evolution. Analyses of TCRδ chains in a broad range of vertebrate lineages over the past decade...
Topics
- Animals
- Biological Evolution
- Genetic Variation
- Humans
- Phylogeny
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Vertebrates