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Article

Evolution of antigen binding receptors.

Annual review of immunology - 1 Jan 1999

Litman G W, Anderson M K, Rast J P

Abstract excerpt

This review addresses issues related to the evolution of the complex multigene families of antigen binding receptors that function in adaptive immunity. Advances in molecular genetic technology now permit the study of immunoglobulin (Ig) and T cell receptor (TCR) genes in many species that are not commonly studied yet represent critical branch points in vertebrate phylogeny. Both Ig and TCR genes have been...

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Identifiers

PMID: 10358755
DOI: 10.1146/annurev.immunol.17.1.109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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