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Article

Diversity and evolution of T-cell receptor variable region genes in mammals and birds.

Immunogenetics - 1 Dec 1999

Su C, Jakobsen I, Gu X, Nei M

Abstract excerpt

The receptor of a T lymphocyte (TCR) recognizes nonself antigens in the company of major histocompatibility complex (MHC) molecules presented to it by the antigen-presenting cell. The variable region of TCR is encoded by either a concatenation of variable region (TCR-V), diversity region (TCR-D), and joining region (TCR-J) genes, or a concatenation of TCR-V and TCR-J genes. The TCR-V genes exist as a multigene...

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PMID: 10630294
DOI: 10.1007/s002510050606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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