The evolutionary and structural 'logic' of antigen receptor diversity.

doi:10.1016/j.smim.2004.08.003

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Article

The evolutionary and structural 'logic' of antigen receptor diversity.

Seminars in immunology - 1 Aug 2004

Davis Mark M

Abstract excerpt

Most vertebrate species utilize antibody and T-cell receptor (TCR) genes to create a vast repertoire of antigen sensor molecules on their B and T lymphocytes, respectively. While the organization of these genes exhibits substantial variation between species, one common theme is that, in almost ev...

Topics

Amino Acid Sequence
Animals
Antibody Diversity
Evolution, Molecular
Genes, Immunoglobulin
Genes, T-Cell Receptor
Genetic Variation
Humans
Models, Immunological
Molecular Sequence Data
Receptors, Antigen
Vertebrates

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