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Article

Associations of MMP1, MMP2 and MMP3 Genes Polymorphism with Coal Workers' Pneumoconiosis in Chinese Han Population.

International journal of environmental research and public health - 30 Oct 2015

Ji Xiaoming, Wang Lijuan, Wu Baiqun, Han Ruhui, Han Lei, Wang Ting, Yang Jingjin, Ni Chunhui

Abstract excerpt

Coal workers' pneumoconiosis (CWP) has been associated with abnormalities in the extracellular matrix remodeling, as well as aberrant matrix metalloproteinases (MMPs) in lung tissues. We investigated the association of three functional polymorphisms in MMP gene promoters (MMP1 rs1799750, MMP2 rs2285053 and MMP3 rs522616) with the risk of CWP. A total of 693 CWP cases and 690 controls were included in a...

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Identifiers

PMID: 26528997
DOI: 10.3390/ijerph121113901
PMCID: PMC4661622

Genes

MMP3
MMP1
MMP2

Provenance

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