Article
Heterozygous Ins/Del genotype of the CASP8 rs3834129 polymorphism significantly decreases the risk of coal workers' pneumoconiosis in a Chinese Han population: a case-control study.
European review for medical and pharmacological sciences - 1 Dec 2021
Hou Z-F, Wang H, Ji S-Q, Kang D-M, Zhao H, Guo Y, Ma J-F, Wang J-Z, Ma X, Gao Y
Abstract excerpt
OBJECTIVE: Coal workers' pneumoconiosis (CWP) is a chronic inflammatory and fibrotic pulmonary disease that involves a complex interaction of multiple environmental and genetic factors. Polymorphism, as a genetic factor, may affect the onset of the disease in susceptible populations. The present study investigated the association between the polymorphisms of six genes and CWP risk in a Chinese Han population....
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