Article
Polymorphisms in SELE gene and risk of coal workers' pneumoconiosis in Chinese: a case-control study.
PloS one - 1 Jan 2013
Wang Ting, Ji Xiaoming, Luo Chen, Fan Jingjing, Hou Zhiguo, Chen Minjuan, Han Ruhui, Ni Chunhui
Abstract excerpt
BACKGROUND: Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic nodular lesions that usually lead to progressive fibrosis. Inflammation is the first step in the development of CWP. E-selectin, an adhesion molecule, is involved in the development of various inflammatory diseases. METHODS: We investigated the association between the functional polymorphisms in SELE and...
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