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Article

Understanding the function of ABCA7 in Alzheimer's disease.

Biochemical Society transactions - 1 Oct 2015

Li Hongyun, Karl Tim, Garner Brett

Abstract excerpt

ATP-binding cassette transporter A7 (ABCA7) is highly expressed in the brain. Recent genome-wide association studies (GWAS) identify ABCA7 single nt polymorphisms (SNPs) that increase Alzheimer's disease (AD) risk. It is now important to understand the true function of ABCA7 in the AD context. We have begun to address this using in vitro and in vivo AD models. Our initial studies showed that transient...

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Source

Identifiers

PMID: 26517904
DOI: 10.1042/BST20150105

Genes

ABCA7
APP
PDGFB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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