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ABC Transporters Are Key Players in Alzheimer’s Disease

21 Nov 2017

Abstract excerpt

Human ATP-binding cassette (ABC) transporters mediate a critical function in the cell, namely the transport of molecules across lipid membranes. Associated to their ubiquitous tissue distribution, they are key players in cellular homeostasis but also potential causative or contributing factors for many pathologies, including Alzheimer's disease (AD). In the central nervous system (CNS), numerous ABC transporters...

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PMID: 29171999
DOI: 10.3233/jad-170639

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