Article
ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status.
Neuroscience letters - 27 Nov 2013
Vasquez Jared B, Fardo David W, Estus Steven
Abstract excerpt
Genome-wide association studies (GWAS) have implicated a series of single nucleotide polymorphisms (SNPs) in Alzheimer's disease (AD) risk. Elucidating the function of these SNPs is critical to identify the underlying pathways and, potentially, novel therapeutic agents. SNPs within the gene ATP binding cassette A7 (ABCA7) reached significance in these studies, warranting investigation into their actions. Here, we...
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