Article
The centriolar protein CPAP G-box: an amyloid fibril in a single domain.
Biochemical Society transactions - 1 Oct 2015
Cutts Erin E, Inglis Alison, Stansfeld Phillip J, Vakonakis Ioannis, Hatzopoulos Georgios N
Abstract excerpt
Centrioles are evolutionarily conserved cylindrical cell organelles with characteristic radial symmetry. Despite their considerable size (400 nm × 200 nm, in humans), genetic studies suggest that relatively few protein components are involved in their assembly. We recently characterized the molecular architecture of the centrosomal P4.1-associated protein (CPAP), which is crucial for controlling the centriolar...
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