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Article

Stepwise evolution of the centriole-assembly pathway.

Journal of cell science - 1 May 2010

Carvalho-Santos Zita, Machado Pedro, Branco Pedro, Tavares-Cadete Filipe, Rodrigues-Martins Ana, Pereira-Leal José B, Bettencourt-Dias Mónica

Abstract excerpt

The centriole and basal body (CBB) structure nucleates cilia and flagella, and is an essential component of the centrosome, underlying eukaryotic microtubule-based motility, cell division and polarity. In recent years, components of the CBB-assembly machinery have been identified, but little is known about their regulation and evolution. Given the diversity of cellular contexts encountered in eukaryotes, but the...

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Source

Identifiers

PMID: 20392737
DOI: 10.1242/jcs.064931

Genes

PLK4
CPAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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