Article
Genetic Polymorphism of MDM2 SNP309 in Patients with Helicobacter Pylori-Associated Gastritis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Tongtawee Taweesak, Dechsukhum Chavaboon, Leeanansaksiri Wilairat, Kaewpitoon Soraya, Kaewpitoon Natthawut, Loyd Ryan A, Matrakool Likit, Panpimanmas Sukij
Abstract excerpt
BACKGROUND: Helicobacter pylori plays an important role in gastric cancer, which has a relatively low inciduence in Thailand. MDM2 is a major negative regulator of p53, the key tumor suppressor involved in tumorigenesis of the majority of human cancers. Whether its expression might explain the relative lack of gastric cancer in Thailand was assessed here. MATERIALS AND METHODS: This single-center study was...
Topics
- Asian People
- DNA
- Female
- Gastric Mucosa
- Gastritis
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Male
- Middle Aged