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Article

Effects of p53 codon 72 and MDM2 SNP309 polymorphisms on gastric cancer risk among the Iranian population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Moradi Mohammad-Taher, Salehi Zivar, Aminian Keyvan, Yazdanbod Abbas

Abstract excerpt

BACKGROUND: Development of gastric cancer (GC) is a multistep process that requires alterations in the expression of oncogenes and tumor suppressor genes, occurring over several decades. The p53 tumor suppressor protein is involved in cell-cycle control, apoptosis and DNA repair. One of the most important regulators of p53 is MDM2, which acts as a negative regulator in the p53 pathway. Based on the key role of...

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Identifiers

PMID: 25227851
DOI: 10.7314/apjcp.2014.15.17.7413

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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