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Article

A method for CRISPR/Cas9 mutation of genes in fathead minnow (Pimephales promelas).

Aquatic toxicology (Amsterdam, Netherlands) - 1 May 2020

Maki Jennifer A, Cavallin Jenna E, Lott Kevin G, Saari Travis W, Ankley Gerald T, Villeneuve Daniel L

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 genome editing allows for the disruption or modification of genes in a multitude of model organisms. In the present study, we describe and employ the method for use in the fathead minnow (Pimephales promelas), in part, to assist in the development and validation of adverse outcome pathways (AOPs). The gene coding for an enzyme responsible for...

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Identifiers

PMID: 32160575
DOI: 10.1016/j.aquatox.2020.105464
PMCID: PMC7280908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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