Article
Association between RAD 51 rs1801320 and susceptibility to glioblastoma.
Journal of neuro-oncology - 1 Jan 2016
Franceschi S, Tomei S, Mazzanti C M, Lessi F, Aretini P, La Ferla M, De Gregorio V, Pasqualetti F, Zavaglia K, Bevilacqua G, Naccarato A G
Abstract excerpt
Glioblastoma is the most common and aggressive malignant primary brain tumor. Despite decades of research and the advent of new therapies, patients with glioblastoma continue to have a very poor prognosis. Radiation therapy has a major role as adjuvant treatment for glioblastoma following surgical resection. Many studies have shown that polymorphisms of genes involved in pathways of DNA repair may affect the...
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