Article
Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility.
BMC cancer - 10 May 2013
Zhao Peng, Zou Peng, Zhao Lin, Yan Wei, Kang Chunsheng, Jiang Tao, You Yongping
Abstract excerpt
BACKGROUND: Genetic variations in DNA double-strand break repair genes can influence the ability of a cell to repair damaged DNA and alter an individual's susceptibility to cancer. We studied whether polymorphisms in DNA double-strand break repair genes are associated with an increased risk of glioma development. METHODS: We genotyped 10 potentially functional single nucleotide polymorphisms (SNPs) in 7 DNA...
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