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Article

A Comprehensive Meta-analysis of Genetic Associations Between Key Polymorphic Loci in DNA Repair Genes and Glioma Risk.

Molecular neurobiology - 1 Mar 2017

Qi Ling, Yu Hong-Quan, Zhang Yu, Ding Li-Juan, Zhao Dong-Hai, Lv Peng, Wang Wei-Yao, Xu Ye

Abstract excerpt

Genetic variants found in DNA repair genes (ERCC1, rs3212986; ERCC2, rs13181; ERCC4, rs1800067; ERCC5, rs17655; XRCC1, rs1799782, rs25487, ; XRCC3, ) have been reported to have an ambivalent association with the development of glioma. In the present study, a meta-analysis was conducted to confirm the relationship, taking heterogeneity of population into consideration. We analyzed 21 articles of 6...

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Topics

Brain Neoplasms
DNA Repair
Genetic Association Studies
Genetic Loci
Genetic Predisposition to Disease
Genetic Variation
Glioma
Humans
Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 26843108
DOI: 10.1007/s12035-016-9725-5

Genes

ERCC1
ERCC2
ERCC4
ERCC5
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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