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Article

Association of Glutathione S-Transferase P-1 (GSTP-1) rs1695 polymorphism with overall survival in glioblastoma patients treated with combined radio-chemotherapy.

Investigational new drugs - 1 Apr 2018

Pasqualetti Francesco, Gonnelli Alessandra, Cantarella Martina, Delishaj Durim, Molinari Alessandro, Ortenzi Valerio, Carbone Francesco, Montrone Sabrina, Ursino Stefano, Franceschi Sara, Morganti Riccardo, Orlandi Paola, Di Desidero Teresa, Mazzanti Chiara Maria, Zavaglia Katia, Naccarato Antonio Giuseppe, Bocci Guido, Paiar Fabiola

Abstract excerpt

Glioblastoma (GBM) is the most frequent malignant primary brain tumor in adults and, despite recent advances, the prognosis for this cancer remains dismal. The aims of this study were to test the influence of XRCC1 rs25487, XRCC3 rs861539, XRCC3 rs1799794, RAD51 rs1801320 and GSTP-1 rs1695 single nucleotide polymorphisms on progression free survival (PFS) and overall survival (OS) in GBM patients treated with...

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Source

Identifiers

PMID: 28965273
DOI: 10.1007/s10637-017-0516-2

Genes

XRCC3
RAD51
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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