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Polymorphisms of DNA Repair Genes and Risk of Glioma

15 Aug 2004

Abstract excerpt

DNA repair genes play a major role in maintaining genomic stability through different repair pathways that are mediated by cell cycle control genes such as p53. We found previously that glioma patients were susceptible to gamma-ray-induced chromosomal breaks, which may be influenced by genetic variation in genes involved in DNA strand breaks, such as XRCC1 in single-strand break repair, XRCC3 and RAD51 in...

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PMID: 15313891
DOI: 10.1158/0008-5472.can-03-2181

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Source receipt: pubmed, retrieved 7 Sept 2026.

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