Article
Association between the XRCC1 polymorphisms and glioma risk: a meta-analysis of case-control studies.
PloS one - 1 Jan 2013
Jiang Lei, Fang Xiao, Bao Yi, Zhou Jue-Yu, Shen Xiao-Yan, Ding Mao-Hua, Chen Yi, Hu Guo-Han, Lu Yi-Cheng
Abstract excerpt
BACKGROUND: X-ray repair cross-complementing group 1 (XRCC1) is one of the DNA repair genes encoding a scaffolding protein that participate in base excision repair (BER) pathway. However, studies on the association between polymorphisms in this gene and glioma have yielded conflicting results. This meta-analysis was performed to derive a more precise estimation between XRCC1 polymorphisms (Arg399Gln, Arg194Trp,...
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