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Functional disruption of human leukocyte antigen II in human embryonic stem cell

27 Oct 2015

Abstract excerpt

BACKGROUND: Theoretically human embryonic stem cells (hESCs) have the capacity to self-renew and differentiate into all human cell types. Therefore, the greatest promise of hESCs-based therapy is to replace the damaged tissues of patients suffering from traumatic or degenerative diseases by the exact same type of cells derived from hESCs. Allograft immune rejection is one of the obstacles for hESCs-based clinical...

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PMID: 26506955
DOI: 10.1186/s40659-015-0051-6

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