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Article

ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study.

Scientific reports - 16 Feb 2018

Chen Chung-Jen, Tseng Chia-Chun, Yen Jeng-Hsien, Chang Jan-Gowth, Chou Wen-Cheng, Chu Hou-Wei, Chang Shun-Jen, Liao Wei-Ting

Abstract excerpt

Although many genome-wide association studies (GWASs) of hyperuricemia or gout have been reported, the related genetic factors and the mechanisms from hyperuricemia to gouty attack remain unclear. This study aimed to identify genetic factors and pathogenesis of gout from hyperuricemia by genome-wide association study (GWAS). 747 gout patients, 747 hyperuricemia and 2071 age-matched controls were recruited and...

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Topics

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to ABCG2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Gout, Hyperuricemia, Uric Acid

Share to Hyperuricemia

Share to Inflammasome and immune disorders

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 29453348
DOI: 10.1038/s41598-018-21425-7
PMCID: PMC5816657

Genes

ABCG2

Provenance

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